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Genica Health

Australian scientists uncover key genetic drivers behind long COVID

Australian scientists have identified the key genetic drivers behind long COVID, revealing why some people continue to experience debilitating symptoms long after their initial infection.
news-medical.net/news/20251215/Australian-scientists-uncover-key-genetic-drivers-behind-long-COVID.aspx

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Machine learning reveals dental caries heterogeneity in NHANES

A new article published in the Journal of Dental Research explores the development an integrated data-cleaning and subtype discovery pipeline using unsupervised machine learning for comprehensive analysis and visualization of data patterns in the National Health and Nutrition Examination Survey (NHANES) database.
news-medical.net/news/20251211/Machine-learning-reveals-dental-caries-heterogeneity-in-NHANES.aspx

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Bacterial enzyme linked to heart complications in pneumonia

Pneumonia is a disease that burdens the healthcare system with more that 1.2 million emergency room visits each year and more than 41,000 adult deaths in the United States.
news-medical.net/news/20251204/Bacterial-enzyme-linked-to-heart-complications-in-pneumonia.aspx

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FOLFIRINOX shows promise as a second-line option for advanced biliary tract cancer

Biliary tract cancers, including intrahepatic, perihilar, and extrahepatic cholangiocarcinoma and gallbladder cancer, are among the most aggressive gastrointestinal malignancies.
news-medical.net/news/20251127/FOLFIRINOX-shows-promise-as-a-second-line-option-for-advanced-biliary-tract-cancer.aspx

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Neoantigens-loaded DC vaccines show strong potential to overcome tumor resistance

Despite the success of immune checkpoint inhibitors in revolutionizing oncology, their benefits remain limited to a small fraction of patients.
news-medical.net/news/20251119/Neoantigens-loaded-DC-vaccines-show-strong-potential-to-overcome-tumor-resistance.aspx

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Study highlights need for XDP specific diagnostic assays

Scientists at Brigham and Women's Hospital and Harvard Medical School have developed a targeted genetic test to improve diagnosis for X-linked dystonia-parkinsonism (XDP), a rare and disabling movement disorder that affects primarily men of Filipino ancestry.
news-medical.net/news/20251117/Study-highlights-need-for-XDP-specific-diagnostic-assays.aspx

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Innovative test for Lyme disease offers hope for faster diagnosis

Researchers at Dartmouth Hitchcock Medical Center have developed a way to diagnose Lyme disease earlier and more accurately than traditional testing methods.
news-medical.net/news/20251114/Innovative-test-for-Lyme-disease-offers-hope-for-faster-diagnosis.aspx

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New technique revolutionizes the design of drugs that target ion channels

An international team involving the Institute of Chemical Research, a joint centre of the University of Seville and the Spanish National Research Council, has developed a new technique that will accelerate the design of drugs that target ion channels, a type of cell membrane protein involved in numerous diseases, ranging from psychiatric disorders to various types of cancer.
news-medical.net/news/20251114/New-technique-revolutionizes-the-design-of-drugs-that-target-ion-channels.aspx

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New approach revives DNA from historic medical tissues

Research institutions around the world house valuable genetic information that could help unlock countless medical mysteries. However, because DNA degrades over time, it is difficult for researchers to analyze DNA samples older than 20 years using conventional analytical approaches.
news-medical.net/news/20251113/New-approach-revives-DNA-from-historic-medical-tissues.aspx

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Study links common Epstein-Barr virus to autoimmune lupus

One of humanity's most ubiquitous infectious pathogens bears the blame for the chronic autoimmune condition called systemic lupus erythematosus or, colloquially, lupus, Stanford Medicine investigators and their colleagues have found.
news-medical.net/news/20251112/Study-links-common-Epstein-Barr-virus-to-autoimmune-lupus.aspx

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AI chat box helps investigate complex biology in English language

Using sophisticated RNA sequencing technology, biomedical researchers can measure the activity of our genes across millions of single cells, creating detailed maps of tissues, organs, and diseases.
news-medical.net/news/20251111/AI-chat-box-helps-investigate-complex-biology-in-English-language.aspx

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Exploring endogenous retroviruses as hidden drivers of alcohol use disorder

Alcohol use disorder (AUD), characterized by uncontrollable alcohol consumption due to physical and psychological dependence, affects approximately 14.1 million people in the U.S.
news-medical.net/news/20251107/Exploring-endogenous-retroviruses-as-hidden-drivers-of-alcohol-use-disorder.aspx

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Undergraduate researcher uncovers molecular secrets of HPV’s cancer-causing mechanisms

When Sean Fletcher walked into Sam Biswas' Medical and Molecular Sciences (MMSC) lab at the University of Delaware College of Health Sciences during the summer of his first year, he had no research or laboratory experience.
news-medical.net/news/20251031/Undergraduate-researcher-uncovers-molecular-secrets-of-HPVe28099s-cancer-causing-mechanisms.aspx

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Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K–AKT pathway

Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.
news-medical.net/news/20251030/Thiostrepton-suppresses-rhabdomyosarcoma-progression-by-targeting-the-PI3Ke28093AKT-pathway.aspx

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Unlocking memory: The role of epigenetics in memory expression

Our experiences leave traces in the brain, stored in small groups of cells called "engrams". Engrams are thought to hold the information of a memory and are reactivated when we remember, which makes them very interesting to research on memory and age- or trauma-related memory loss.
news-medical.net/news/20251029/Unlocking-memory-The-role-of-epigenetics-in-memory-expression.aspx

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UC Irvine receives funding for clinical trial of neural stem cell therapy for Huntington's disease

Leslie M. Thompson, Donald Bren Professor of psychiatry and human behavior as well as neurobiology and behavior at the University of California, Irvine, has received an $11,999,933 grant from the California Institute for Regenerative Medicine for an unprecedented clinical trial of a novel neural stem cell therapy for Huntington's disease.
news-medical.net/news/20251212/UC-Irvine-receives-funding-for-clinical-trial-of-neural-stem-cell-therapy-for-Huntingtons-disease.aspx

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Machine learning models can help diagnose ALS earlier from a blood sample

Using machine learning models, researchers at Michigan Medicine have identified a potential way to diagnose amyotrophic lateral sclerosis, or ALS, earlier from a blood sample, a study suggests.
news-medical.net/news/20251210/Machine-learning-models-can-help-diagnose-ALS-earlier-from-a-blood-sample.aspx

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Untreated restless legs syndrome may increase Parkinson's disease risk

Restless legs syndrome (RLS) is a common neurological sleep disorder characterized by an uncontrollable urge to move the legs, often worsening at night.
news-medical.net/news/20251202/Untreated-restless-legs-syndrome-may-increase-Parkinsons-disease-risk.aspx

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AMI urges stronger and more equitable global action plan on antimicrobial resistance

In World Antimicrobial Resistance Awareness Week (WAAW), Applied Microbiology International (AMI) has urged global policymakers to strengthen the revised Global Action Plan on Antimicrobial Resistance (GAP-AMR), calling for a more inclusive, clear and equitable approach to tackling one of the world's most urgent health challenges.
news-medical.net/news/20251120/AMI-urges-stronger-and-more-equitable-global-action-plan-on-antimicrobial-resistance.aspx

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New AMR portal provides large-scale curated data to to advance antimicrobial resistance research

Antimicrobial resistance (AMR) is a growing health challenge, reducing the effectiveness of life-saving treatments and increasing the risk of complications from routine medical procedures.
news-medical.net/news/20251118/New-AMR-portal-provides-large-scale-curated-data-to-to-advance-antimicrobial-resistance-research.aspx

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Uncovering hidden causes of recurrent pregnancy loss with optical genome mapping

Pregnancy loss may occur in as many as 25% of all pregnancies. Most of these losses occur in the first trimester, and about half are caused by genetic or chromosomal issues.
news-medical.net/news/20251114/Uncovering-hidden-causes-of-recurrent-pregnancy-loss-with-optical-genome-mapping.aspx

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New molecular test revolutionizes fungal infection diagnosis

Certain serious fungal infections occur in regions of the United States with specific environments and are often tied to soil exposure.
news-medical.net/news/20251114/New-molecular-test-revolutionizes-fungal-infection-diagnosis.aspx

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Enhancing the cancer-immunity cycle through innovative vaccines

Therapeutic cancer vaccines have experienced a remarkable resurgence over the past decade, representing a paradigm shift in oncology toward harnessing the immune system's intrinsic ability to combat malignancies.
news-medical.net/news/20251114/Enhancing-the-cancer-immunity-cycle-through-innovative-vaccines.aspx

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Carolina Molecular partners with Pixelgen, becomes first US certified service provider for Pixelgen Proxiome Kit - Pixelgen Technologies

Carolina Molecular Inc., a leading molecular testing services laboratory, and Pixelgen Technologies AB announced today a partnership to expand access to cutting-edge 3D protein interactomics capabilities to researchers and clinicians in the United States. Carolina Molecular will be the first certified U.S. service provider for Pixelgen.
news-medical.net/news/20251113/Carolina-Molecular-partners-with-Pixelgen-becomes-first-US-certified-service-provider-for-Pixelgen-Proxiome-Kit-Pixelgen-Technologies.aspx

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Breakthroughs in theranostic nanomaterials for traumatic brain injury management

Traumatic brain injury (TBI) remains one of the most pressing public health challenges, leaving millions with lasting disabilities each year.
news-medical.net/news/20251112/Breakthroughs-in-theranostic-nanomaterials-for-traumatic-brain-injury-management.aspx

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MGI Tech joins forces with SAMRC and DSTI to launch South Africa’s 110K Human Genome Program and unveil Africa’s first DNBSEQ-T7, ushering in a new era in African genomics

The DNBSEQ-T7 sequencing platform and 110K Human Genome Program are transforming South Africa's genomic landscape, promoting local expertise and health equity.
news-medical.net/news/20251111/MGI-Tech-joins-forces-with-SAMRC-and-DSTI-to-launch-South-Africae28099s-110K-Human-Genome-Program-and-unveil-Africae28099s-first-DNBSEQ-T7-ushering-in-a-new-era-in-African-genomics.aspx

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Study finds high intake of ultra-processed foods tied to reduced DNA methylation

Women who consumed more ultra-processed foods (UPFs) showed distinct DNA methylation patterns, mostly reduced across key gene regions. These exploratory findings suggest that high UPF intake may influence gene regulation through epigenetic mechanisms.
news-medical.net/news/20251104/Study-finds-high-intake-of-ultra-processed-foods-tied-to-reduced-DNA-methylation.aspx

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Massive cross-ancestry study explains why obesity risks differ around the world

A massive cross-ancestry genetic study involving over 839,000 adults identified 13 genes linked to obesity, including five never before associated with the condition. The findings highlight how global genetic diversity can uncover new biological pathways and potential treatment targets for obesity.
news-medical.net/news/20251031/Massive-cross-ancestry-study-explains-why-obesity-risks-differ-around-the-world.aspx

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Global Virus Network announces the addition of three new Centers of Excellence

The Global Virus Network (GVN), a coalition of leading medical virologists representing 80+ Centers of Excellence and Affiliates in 40+ countries, today announced the addition of three new Centers of Excellence: the USF Health Institute for Translational Virology and Innovation at the University of South Florida (USF) in Tampa, Florida, USA, the Department of Microbiology, Immunology and Parasitology at the Federal University of São Paulo (UNIFESP) in Brazil, and the Pathogen Research Centre (PaRC) at Western University in Canada.
news-medical.net/news/20251030/Global-Virus-Network-announces-the-addition-of-three-new-Centers-of-Excellence.aspx

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Harnessing bioinformatics to fast-track the discovery of spinal cord injury drug

Spinal cord injury (SCI) remains a major unmet medical challenge, often resulting in permanent paralysis and disability with no effective treatments.
news-medical.net/news/20251029/Harnessing-bioinformatics-to-fast-track-the-discovery-of-spinal-cord-injury-drug.aspx

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