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Liquid biopsy enables rapid diagnosis of Burkitt lymphoma in Africa
In a study published today in Nature Medicine, researchers from the University of Oxford and the Muhimbili University of Health and Allied Sciences (MUHAS) in Dar es salaam, Tanzania have shown that a minimally invasive "liquid biopsy" test can diagnose Burkitt lymphoma rapidly and accurately in sub-Saharan Africa, where delays in traditional testing often prove fatal.
news-medical.net/news/20260319/Liquid-biopsy-enables-rapid-diagnosis-of-Burkitt-lymphoma-in-Africa.aspx
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Protein MIIP suppresses colorectal cancer by regulating immune cell signaling
Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and limited responses to immunotherapy in most patients.
news-medical.net/news/20260316/Protein-MIIP-suppresses-colorectal-cancer-by-regulating-immune-cell-signaling.aspx
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Machine learning detects early brain changes linked to Alzheimer's disease
Worcester Polytechnic Institute (WPI) researchers have used a form of artificial intelligence (AI) to analyze anatomical changes in the brain and predict Alzheimer's disease with nearly 93% accuracy.
news-medical.net/news/20260305/Machine-learning-detects-early-brain-changes-linked-to-Alzheimers-disease.aspx
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Accelerating rare disease diagnosis with Mondo
Coryssa Barnes, of Henderson, N.C., welcomed her first child, Ezra, in 2020. At four months old, he was unable to sit without support. As time went on, he failed to reach other developmental milestones, prompting his worried parents to consult several medical experts.
news-medical.net/news/20260302/Accelerating-rare-disease-diagnosis-with-Mondo.aspx
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Novel antimicrobial peptides from dromedary camels offer hope against antibiotic resistance
Antimicrobial resistance poses a growing global health crisis, with few new antibiotics in development.
news-medical.net/news/20260222/Novel-antimicrobial-peptides-from-dromedary-camels-offer-hope-against-antibiotic-resistance.aspx
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New approach better predicts chemotherapy response in patients with triple-negative breast cancer
Researchers at The University of Texas MD Anderson Cancer Center have developed a new computational approach designed to better account for changes in gene expression within tumors relative to their unique microenvironments.
news-medical.net/news/20260217/New-approach-better-predicts-chemotherapy-response-in-patients-with-triple-negative-breast-cancer.aspx
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Innate immune priming may evolve into a broadly applicable infection-prevention strategy
Secondary infections caused by bacteria or viruses during hospital care remain a long-standing global challenge, despite advances in modern medicine.
news-medical.net/news/20260216/Innate-immune-priming-may-evolve-into-a-broadly-applicable-infection-prevention-strategy.aspx
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New spatial omics platform advances biomedical research in Spain
Spatial omics is a new generation of technologies that allow scientists to study cells in their original location within tissues (without isolating or moving them from their environment).
news-medical.net/news/20260209/New-spatial-omics-platform-advances-biomedical-research-in-Spain.aspx
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New analysis reveals hidden complexity in the vaginal microbiome
For decades, gynecological tests have relied on a simplified view of the vaginal microbiome, categorizing bacteria as either "good" or "bad."
news-medical.net/news/20260206/New-analysis-reveals-hidden-complexity-in-the-vaginal-microbiome.aspx
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Reprogrammed neutrophils promote tumor growth
Predicting tumor progression is one of the major challenges in oncology. Scientists at the University of Geneva (UNIGE) and the Ludwig Institute for Cancer Research have discovered that neutrophils, a type of immune cell, undergo reprogramming when they come into contact with the tumor ecosystem and contribute to its progression.
news-medical.net/news/20260205/Reprogrammed-neutrophils-promote-tumor-growth.aspx
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NIH grant disruptions slow down breast cancer research
Inside a cancer research laboratory on the campus of Harvard Medical School, two dozen small jars with pink plastic lids sat on a metal counter. Inside these humble-looking jars is the core of Joan Brugge's current multiyear research project.
news-medical.net/news/20260203/NIH-grant-disruptions-slow-down-breast-cancer-research.aspx
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Genetic ancestry influences tumor biology and survival in head and neck cancers
Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help explain why African-American patients survive for half as long as their counterparts of European ancestry, according to a new review study led by researchers from the University of Maryland School of Medicine's (UMSOM) Institute for Genome Sciences (IGS) and the University of Maryland Greenebaum Comprehensive Cancer Center (UMGCCC).
news-medical.net/news/20260131/Genetic-ancestry-influences-tumor-biology-and-survival-in-head-and-neck-cancers.aspx
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AI applied to abdominal imaging can help predict fall risk in adults
Artificial intelligence (AI) applied to abdominal imaging can help predict adults at higher risk of falling as early as middle age, a new Mayo Clinic study shows.
news-medical.net/news/20260122/AI-applied-to-abdominal-imaging-can-help-predict-fall-risk-in-adults.aspx
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New DNA tests reveal hidden biological traces on Renaissance art
DNA analysis of cultural artifacts shows diverse biological profiles, but contamination and mixed signals complicate historical lineage interpretation.
news-medical.net/news/20260108/New-DNA-tests-reveal-hidden-biological-traces-on-Renaissance-art.aspx
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Study demonstrates significant changes in gut bacteria at the onset of IBD
Patients experience significant changes in gut bacteria at the onset of inflammatory bowel disease (IBD), a new international study has found - offering new hope for earlier diagnosis and future treatments.
news-medical.net/news/20251223/Study-demonstrates-significant-changes-in-gut-bacteria-at-the-onset-of-IBD.aspx
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AlphaFold Database expands with millions of predicted protein complexes
A new collaboration between EMBL's European Bioinformatics Institute (EMBL-EBI), Google DeepMind, NVIDIA, and Seoul National University has made millions of AI-predicted protein complex structures openly available through the AlphaFold Database.
news-medical.net/news/20260317/AlphaFold-Database-expands-with-millions-of-predicted-protein-complexes.aspx
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STING agonists exert potent antitumor effects against nervous system tumors
The cGAS-STING signaling pathway has emerged as a major focus in cancer immunotherapy because it stimulates interferon production and enhances antitumor immune responses.
news-medical.net/news/20260309/STING-agonists-exert-potent-antitumor-effects-against-nervous-system-tumors.aspx
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MERLIN algorithm unlocks immune cell location memory in organs
A new AI-based method reconstructs spatial information about where immune cells were originally located in an organ, even after these cells have been removed from the tissue and analyzed individually.
news-medical.net/news/20260302/MERLIN-algorithm-unlocks-immune-cell-location-memory-in-organs.aspx
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Building an affordable toolkit for healthy aging
As people age, they experience a gradual decline in intrinsic capacity (IC), the combined physical and mental abilities that support independence and health. The World Health Organization recognizes IC as a central indicator of resilience in aging, yet no affordable, validated tool exists to measure it.
news-medical.net/news/20260227/Building-an-affordable-toolkit-for-healthy-aging.aspx
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DeepRare AI helps shorten the rare disease diagnostic journey with evidence-linked predictions
Researchers developed DeepRare, an LLM-driven multi-agent diagnostic system that integrates clinical descriptions, phenotype data, and genomic information to improve rare disease identification.
Across thousands of cases, the system showed higher diagnostic recall than existing AI tools and clinicians in benchmark testing, while providing traceable reasoning linked to medical evidence.
news-medical.net/news/20260219/DeepRare-AI-helps-shorten-the-rare-disease-diagnostic-journey-with-evidence-linked-predictions.aspx
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Insilico Medicine and MSK collaborate to discover new drug targets for gastroesophageal malignancies
Insilico Medicine ("Insilico", 3696.HK), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, and Memorial Sloan Kettering Cancer Center (MSK) have entered into a collaborative research agreement aimed at discovering new therapeutic targets for gastroesophageal malignancies.
news-medical.net/news/20260217/Insilico-Medicine-and-MSK-collaborate-to-discover-new-drug-targets-for-gastroesophageal-malignancies.aspx
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@Genica1
Early bone molecular changes signal osteoarthritis progression
Osteoarthritis often goes undetected until cartilage damage is advanced, limiting treatment options. A new study shows that molecular changes in subchondral bone occur earlier and can signal disease progression before cartilage loss.
news-medical.net/news/20260210/Early-bone-molecular-changes-signal-osteoarthritis-progression.aspx
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Chronic brain compression triggers neuron death through multiple pathways
To think, feel, talk and move, neurons send messages through electrical signals in the brain and spinal cord.
news-medical.net/news/20260209/Chronic-brain-compression-triggers-neuron-death-through-multiple-pathways.aspx
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European collaboration transforms immune cell data into cancer biomarkers
World Cancer Day, marked on 4 February, is an international day dedicated to raising awareness of cancer, and to encouraging its prevention, detection and treatment.
news-medical.net/news/20260206/European-collaboration-transforms-immune-cell-data-into-cancer-biomarkers.aspx
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Molecular signature of sleeping nociceptors offers new pain targets
Researchers from the Centre for Addiction and Mental Health (CAMH) and the Institute of Neurophysiology at Uniklinik RWTH Aachen in Germany have deciphered the molecular signature of so-called sleeping nociceptors-a type of pain-sensing nerve cell that normally remains quiet and does not respond to touch or pressure, but can become overactive and drive chronic pain.
news-medical.net/news/20260204/Molecular-signature-of-sleeping-nociceptors-offers-new-pain-targets.aspx
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Bat viruses in Indochina Peninsula reveal viral diversity, PEDV origins, and spillover risks
Bats, critical reservoirs of viruses with significant cross-species spillover risks, have long been understudied in the Indochina Peninsula.
news-medical.net/news/20260202/Bat-viruses-in-Indochina-Peninsula-reveal-viral-diversity-PEDV-origins-and-spillover-risks.aspx
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Study offers a practical strategy to enhance effectiveness of immune checkpoint inhibitors
Cancer immunotherapy has transformed modern oncology by harnessing body's own immune system to combat malignant disease.
news-medical.net/news/20260129/Study-offers-a-practical-strategy-to-enhance-effectiveness-of-immune-checkpoint-inhibitors.aspx
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Novel liquid biopsy technology could advance cancer diagnostics and monitoring
A novel liquid biopsy technology is set to advance cancer diagnostics and monitoring by overcoming the long-standing challenge of simultaneously achieving high sensitivity, broad coverage, and simple workflow.
news-medical.net/news/20260114/Novel-liquid-biopsy-technology-could-advance-cancer-diagnostics-and-monitoring.aspx
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MD Anderson and SOPHiA GENETICS join forces to accelerate data-driven cancer care
The University of Texas MD Anderson Cancer Center and SOPHiA GENETICS today announced a strategic collaboration that unites SOPHiA GENETICS' AI-powered analytics with MD Anderson's clinical and scientific expertise to accelerate data-driven cancer care through new tools that can accurately analyze, interpret and translate diagnostic results into clinical practice.
news-medical.net/news/20260107/MD-Anderson-and-SOPHiA-GENETICS-join-forces-to-accelerate-data-driven-cancer-care.aspx
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SARS-CoV-2 manipulates host cell's RNA to weaken the immune response
Researchers at the Federal University of São Paulo (UNIFESP) in Brazil have discovered that SARS-CoV-2, the virus that causes COVID-19, uses a sophisticated tactic to evade the human body's defense system.
news-medical.net/news/20251217/SARS-CoV-2-manipulates-host-cells-RNA-to-weaken-the-immune-response.aspx
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