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Genica NEWS

Reproductive history is associated with women's lifespan and biological aging

A study based on Finnish twins shows that reproductive history is associated, at the population level, with women's lifespan and biological aging.
news-medical.net/news/20260108/Reproductive-history-is-associated-with-womens-lifespan-and-biological-aging.aspx

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New insight into how our bodies keep brain parasite Toxoplasma gondii in check

The parasite that may already live in your brain can infect the very immune cells trying to destroy it, but new UVA Health research reveals how our bodies keep it under control.
news-medical.net/news/20260107/New-insight-into-how-our-bodies-keep-brain-parasite-Toxoplasma-gondii-in-check.aspx

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Research breakthrough could provide a new, non-invasive way to assess retinal health

For the first time, an international research team led by Nanyang Technological University, Singapore (NTU Singapore) has recorded a tiny mechanical "twitch" in living human and rodent eyes at the exact moment a rod photoreceptor detects light.
news-medical.net/news/20260107/Research-breakthrough-could-provide-a-new-non-invasive-way-to-assess-retinal-health.aspx

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New exercise-sensing pathway offers hope for osteoporosis treatment

A research team from the Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine at the University of Hong Kong (HKUMed) has uncovered a key biological mechanism that explains how exercise maintain strong bones, paving the way for novel treatments for osteoporosis and bone loss in people who are unable to engage.
news-medical.net/news/20260106/New-exercise-sensing-pathway-offers-hope-for-osteoporosis-treatment.aspx

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Beer-making leftovers can be transformed into edible scaffolds for lab-grown meat

Yeast left over from brewing beer can be transformed into edible 'scaffolds' for cultivated meat – sometimes known as lab-grown meat – which could offer a more sustainable, cost-effective alternative to current methods, according to a new study from UCL (University College London) researchers.
news-medical.net/news/20260105/Beer-making-leftovers-can-be-transformed-into-edible-scaffolds-for-lab-grown-meat.aspx

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New method can help better assess precision genome editing technology

Scientists and physicians can better assess precision genome editing technology using a new method made public today by St. Jude Children's Research Hospital. Significant amounts of time and resources spent improving CRISPR gene editing technology focus on identifying small off-target sites that pose a safety risk, which is also technically challenging.
news-medical.net/news/20260102/New-method-can-help-better-assess-precision-genome-editing-technology.aspx

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Advancing stem cell regeneration through animal-free culture systems

Intestinal Stem Cells (ISCs) derived from a patient's own cells have garnered significant attention as a new alternative for treating intractable intestinal diseases due to their low risk of rejection.
news-medical.net/news/20251230/Advancing-stem-cell-regeneration-through-animal-free-culture-systems.aspx

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Study demonstrates significant changes in gut bacteria at the onset of IBD

Patients experience significant changes in gut bacteria at the onset of inflammatory bowel disease (IBD), a new international study has found - offering new hope for earlier diagnosis and future treatments.
news-medical.net/news/20251223/Study-demonstrates-significant-changes-in-gut-bacteria-at-the-onset-of-IBD.aspx

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Junk' DNA may hold new clues to Alzheimer’s disease

When most of us think of DNA, we have a vague idea it's made up of genes that give us our physical features, our behavioral quirks, and keep our cells and organs running.
news-medical.net/news/20251218/Junk-DNA-may-hold-new-clues-to-Alzheimere28099s-disease.aspx

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Salutogenic microbes offer new pathways to better health

Viruses and bacteria get a bad rap around the world but now Flinders University experts are identifying the positive 'upside' of powerful benefits that microbes have on human health.
news-medical.net/news/20251216/Salutogenic-microbes-offer-new-pathways-to-better-health.aspx

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Neuron structure variations impact sensory information processing in mice

Closely related subtypes of dopamine-releasing neurons may play entirely separate roles in processing sensory information, depending on their physical structure.
news-medical.net/news/20251216/Neuron-structure-variations-impact-sensory-information-processing-in-mice.aspx

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Australian scientists uncover key genetic drivers behind long COVID

Australian scientists have identified the key genetic drivers behind long COVID, revealing why some people continue to experience debilitating symptoms long after their initial infection.
news-medical.net/news/20251215/Australian-scientists-uncover-key-genetic-drivers-behind-long-COVID.aspx

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SN101 iPSC-derived therapy relieves chronic pain and preserves joints

SereNeuro Therapeutics, a preclinical biotechnology company developing non-opioid pain therapies, unveiled new data today on a novel approach to chronic pain management and joint tissue preservation.
news-medical.net/news/20251212/SN101-iPSC-derived-therapy-relieves-chronic-pain-and-preserves-joints.aspx

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Machine learning reveals dental caries heterogeneity in NHANES

A new article published in the Journal of Dental Research explores the development an integrated data-cleaning and subtype discovery pipeline using unsupervised machine learning for comprehensive analysis and visualization of data patterns in the National Health and Nutrition Examination Survey (NHANES) database.
news-medical.net/news/20251211/Machine-learning-reveals-dental-caries-heterogeneity-in-NHANES.aspx

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EpilepsyGTx raises $33 million Series A to develop single dose gene therapy for focal refractory epilepsy

EpilepsyGTx, a biotechnology company focused on research and development of cutting-edge gene therapies to treat refractory epilepsy, today announced it has raised $33 million in a Series A financing to advance its lead program EPY201 through Phase 1/2a clinical trials.
news-medical.net/news/20251210/EpilepsyGTx-raises-2433-million-Series-A-to-develop-single-dose-gene-therapy-for-focal-refractory-epilepsy.aspx

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New DNA tests reveal hidden biological traces on Renaissance art

DNA analysis of cultural artifacts shows diverse biological profiles, but contamination and mixed signals complicate historical lineage interpretation.
news-medical.net/news/20260108/New-DNA-tests-reveal-hidden-biological-traces-on-Renaissance-art.aspx

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MD Anderson and SOPHiA GENETICS join forces to accelerate data-driven cancer care

The University of Texas MD Anderson Cancer Center and SOPHiA GENETICS today announced a strategic collaboration that unites SOPHiA GENETICS' AI-powered analytics with MD Anderson's clinical and scientific expertise to accelerate data-driven cancer care through new tools that can accurately analyze, interpret and translate diagnostic results into clinical practice.
news-medical.net/news/20260107/MD-Anderson-and-SOPHiA-GENETICS-join-forces-to-accelerate-data-driven-cancer-care.aspx

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Nuclera eProtein Discovery System installed at leading universities in Taiwan

Nuclera, the biotechnology company accelerating drug discovery by providing rapid, easy access to functional proteins through its benchtop eProtein Discovery™ System, today announced that it has completed the first installations of eProtein Discovery in Asia, with systems now operational at the Department of Pharmacy and the Department of Chemistry at the National Taiwan University (NTU) College of Medicine and the Center for Bioscience and Biotechnology and Department of Chemical Engineering at the National Cheng Kung University (NCKU).
news-medical.net/news/20260107/Nuclera-eProtein-Discovery-System-installed-at-leading-universities-in-Taiwan.aspx

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Vitamin A derivative suppresses immune response and cancer vaccine efficacy

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A-all-trans retinoic acid-compromises both the body's normal anti-cancer immune response and, in a different context, the efficacy of a promising type of cancer vaccine.
news-medical.net/news/20260105/Vitamin-A-derivative-suppresses-immune-response-and-cancer-vaccine-efficacy.aspx

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Inhalable nanotherapy can activate the immune system against checkpoint-resistant melanoma

Immune checkpoint molecules play a crucial role in keeping the immune system in balance and preventing an attack on the body's own cells.
news-medical.net/news/20260105/Inhalable-nanotherapy-can-activate-the-immune-system-against-checkpoint-resistant-melanoma.aspx

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First human 'lung-on-chip' model developed using stem cells from a single donor

Researchers at the Francis Crick Institute and AlveoliX have developed the first human 'lung-on-chip' model using stem cells taken from only one person.
news-medical.net/news/20260102/First-human-lung-on-chip-model-developed-using-stem-cells-from-a-single-donor.aspx

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Blocking platelet-activating factor reduces liver damage in cirrhosis

Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified an effective strategy to reduce structural liver damage and improve hepatic vascular function in cirrhosis.
news-medical.net/news/20251219/Blocking-platelet-activating-factor-reduces-liver-damage-in-cirrhosis.aspx

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SARS-CoV-2 manipulates host cell's RNA to weaken the immune response

Researchers at the Federal University of São Paulo (UNIFESP) in Brazil have discovered that SARS-CoV-2, the virus that causes COVID-19, uses a sophisticated tactic to evade the human body's defense system.
news-medical.net/news/20251217/SARS-CoV-2-manipulates-host-cells-RNA-to-weaken-the-immune-response.aspx

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Traumatic brain injury disrupts brain drainage and accelerates Alzheimer’s risk

University of Virginia School of Medicine researchers have uncovered how and why traumatic brain injury (TBI) increases the risk for Alzheimer's disease, and their work suggests a potential way to prevent that increased risk.
news-medical.net/news/20251216/Traumatic-brain-injury-disrupts-brain-drainage-and-accelerates-Alzheimere28099s-risk.aspx

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Scientists engineer AbLecs to overcome cancer's immune evasion tactics

Researchers at MIT and Stanford University have developed a new way to stimulate the immune system to attack tumor cells, using a strategy that could make cancer immunotherapy work for many more patients.
news-medical.net/news/20251216/Scientists-engineer-AbLecs-to-overcome-cancers-immune-evasion-tactics.aspx

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UC Irvine receives funding for clinical trial of neural stem cell therapy for Huntington's disease

Leslie M. Thompson, Donald Bren Professor of psychiatry and human behavior as well as neurobiology and behavior at the University of California, Irvine, has received an $11,999,933 grant from the California Institute for Regenerative Medicine for an unprecedented clinical trial of a novel neural stem cell therapy for Huntington's disease.
news-medical.net/news/20251212/UC-Irvine-receives-funding-for-clinical-trial-of-neural-stem-cell-therapy-for-Huntingtons-disease.aspx

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Exclusive licensing agreement accelerates PHD inhibitor development for anemia in CKD patients

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, and TaiGen Biotechnology, a listed discovery-based and market-focused pharmaceutical company, as well as TaiGen Biopharmaceuticals, its wholly-owned Beijing subsidiary (both referred to as "TaiGen"), today announced an exclusive pipeline out-licensing collaboration.
news-medical.net/news/20251212/Exclusive-licensing-agreement-accelerates-PHD-inhibitor-development-for-anemia-in-CKD-patients.aspx

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Machine learning models can help diagnose ALS earlier from a blood sample

Using machine learning models, researchers at Michigan Medicine have identified a potential way to diagnose amyotrophic lateral sclerosis, or ALS, earlier from a blood sample, a study suggests.
news-medical.net/news/20251210/Machine-learning-models-can-help-diagnose-ALS-earlier-from-a-blood-sample.aspx

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VALANX Biotech establishes Board of Directors

VALANX Biotech (VALANX), a biotech company developing novel antibody-drug-conjugate (ADC) assets enabled by its GoldenSite™ site-specific protein conjugation technology, today announced the formation of its Board of Directors.
news-medical.net/news/20251210/VALANX-Biotech-establishes-Board-of-Directors.aspx

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