Scientists cast new light on how fasting impacts the immune system
New research from The University of Manchester may reshape our understanding of what happens to the immune system when we fast.
news-medical.net/news/20250407/Scientists-cast-new-light-on-how-fasting-impacts-the-immune-system.aspx
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Rutgers researchers develop promising new oral antiviral for COVID-19
Rutgers Health researchers have developed an oral antiviral drug candidate for COVID-19 that could overcome major limitations of Paxlovid, currently the most prescribed oral treatment.
news-medical.net/news/20250403/Rutgers-researchers-develop-promising-new-oral-antiviral-for-COVID-19.aspx
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Cedars-Sinai study investigates diet's role in treating gut disorders
A new study from Cedars-Sinai examined whether a specialized diet could improve symptoms of gastrointestinal disorders linked to an imbalance in gut microbiota.
news-medical.net/news/20250401/Cedars-Sinai-study-investigates-diets-role-in-treating-gut-disorders.aspx
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Glutamate key to unlocking liver regeneration after acute damage
The liver is a vital organ, crucial to digestion, metabolism and the elimination of toxins. It has a unique ability, regeneration, which allows it to replace liver cells damaged by the very toxins that these cells eliminate.
news-medical.net/news/20250326/Glutamate-key-to-unlocking-liver-regeneration-after-acute-damage.aspx
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Novel drug nitisinone could help reduce malaria spread by killing mosquitoes
In the fight against malaria, controlling the mosquito population is crucial.
news-medical.net/news/20250326/Novel-drug-nitisinone-could-help-reduce-malaria-spread-by-killing-mosquitoes.aspx
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Breakthrough DNA delivery system could revolutionize chronic disease treatment
A breakthrough in safely delivering therapeutic DNA to cells could transform treatment for millions suffering from common chronic diseases like heart disease, diabetes, and cancer.
news-medical.net/news/20250325/Breakthrough-DNA-delivery-system-could-revolutionize-chronic-disease-treatment.aspx
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Researchers trace 73% of US Salmonella cases to chicken and vegetables
Researchers used genome sequencing and machine learning to trace the top food sources behind Salmonella infections in the US. Chicken and vegetables emerged as the primary culprits, together accounting for up to 73% of human cases with known sources.
news-medical.net/news/20250323/Researchers-trace-7325-of-US-Salmonella-cases-to-chicken-and-vegetables.aspx
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250,000 whole genomes sequenced for AGD initiative to advance drug discovery
Nashville Biosciences LLC (NashBio), a leading clinical and genomic data company and wholly owned subsidiary of Vanderbilt University Medical Center, and global DNA sequencing giant Illumina Inc. today announced that 250,000 whole genomes have been sequenced for the Alliance for Genomic Discovery (AGD) initiative.
news-medical.net/news/20250321/250000-whole-genomes-sequenced-for-AGD-initiative-to-advance-drug-discovery.aspx
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Melanoma cells use stealth strategy to survive targeted therapy
Researchers have uncovered a stealth survival strategy that melanoma cells use to evade targeted therapy, offering a promising new approach to improving treatment outcomes.
news-medical.net/news/20250320/Melanoma-cells-use-stealth-strategy-to-survive-targeted-therapy.aspx
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New RNA barcoding method tracks gene transfer in microbial communities
In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems.
news-medical.net/news/20250319/New-RNA-barcoding-method-tracks-gene-transfer-in-microbial-communities.aspx
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Biomanufacturing platform offers a sustainable alternative to synthesizing peptide-based pharmaceuticals
To tackle the inequity in medication access, a societal issue especially in developing nations, a team of undergraduate student-researchers at the University of Ottawa has developed a new biomanufacturing platform called Phytogene.
news-medical.net/news/20250318/Biomanufacturing-platform-offers-a-sustainable-alternative-to-synthesizing-peptide-based-pharmaceuticals.aspx
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Discovery of new protein could revolutionize cancer drug delivery
A previously unknown protein in a family of bacteria found in soil and the human gut microbiome has been discovered – which could help drug delivery in cancer treatment.
news-medical.net/news/20250317/Discovery-of-new-protein-could-revolutionize-cancer-drug-delivery.aspx
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SolasCure enrols first patient in a next phase II clinical trial to advance Aurase Wound Gel
SOLASCURE Ltd (SolasCure), a biotechnology company developing a novel treatment to transform chronic wound healing, today announced the initiation of a new Phase II clinical trial, CLEANVLU2.
news-medical.net/news/20250317/SolasCure-enrols-first-patient-in-a-next-phase-II-clinical-trial-to-advance-Aurase-Wound-Gel.aspx
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Study shows impact of statins and aspirin on muscle health in smokers
For current and former smokers, statins may reduce the amount of chest muscle loss, while aspirin may contribute to increased chest muscle loss, according to a new study.
news-medical.net/news/20250313/Study-shows-impact-of-statins-and-aspirin-on-muscle-health-in-smokers.aspx
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Platelet-rich plasma may enhance ovarian rejuvenation and improve egg quality in women
A new research paper was published in Aging (Aging-US) on February 18, 2025, Volume 17, Issue 2, titled "Transcriptomic landscape of cumulus cells from patients <38 years old with a history of poor ovarian response (POR) treated with platelet-rich plasma (PRP)."
news-medical.net/news/20250310/Platelet-rich-plasma-may-enhance-ovarian-rejuvenation-and-improve-egg-quality-in-women.aspx
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New method traces development of nervous system and inner ear cells
Researchers at Karolinska Institutet have developed a method that shows how the nervous system and sensory organs are formed in an embryo.
news-medical.net/news/20250403/New-method-traces-development-of-nervous-system-and-inner-ear-cells.aspx
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NUZ-001 shows positive results in human 3D brain model
Neurizon Therapeutics Limited (“Neurizon”), a clinical-stage biotech company dedicated to advancing treatments for neurodegenerative diseases, is pleased to advise that results from an independent study undertaken in collaboration with Tessara Therapeutics (“Tessara”) will be presented by the group’s Principal Scientist and Alzheimer’s Disease expert, Dr Mark Greenough at the AD/PD 2025 Advances in Sciences & Therapy conference on April 2nd to 3rd.
news-medical.net/news/20250403/NUZ-001-shows-positive-results-in-human-3D-brain-model.aspx
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New research sheds light on prostate cancer resistance mechanisms
According to the American Cancer Society, approximately 1 in 8 men in the U.S. will be diagnosed with prostate cancer during their lifetime.
news-medical.net/news/20250327/New-research-sheds-light-on-prostate-cancer-resistance-mechanisms.aspx
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Researchers develop a reverse genetics system for African swine fever virus
Researchers from the J. Craig Venter Institute (JCVI), the Friedrich-Loeffler-Institut (FLI), and the International Livestock Research Institute (ILRI) have developed a reverse genetics system for African swine fever virus (ASFV).
news-medical.net/news/20250326/Researchers-develop-a-reverse-genetics-system-for-African-swine-fever-virus.aspx
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Study develops fused neural organoids with leptomeninges
A new study in the peer-reviewed journal Stem Cells and Development describes the development of a co-culture system of neural organoids generated from human induced pluripotent stem cells (iPSCs) fused with fetal leptomeninges from mice with fluorescently labeled meninges, called leptomeningeal neural organoid (LMNO) fusions.
news-medical.net/news/20250326/Study-develops-fused-neural-organoids-with-leptomeninges.aspx
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Novel global cooperative phenomena of cell interactions discovered in cervical cancer cells
A Japanese research team has discovered a novel global cooperative phenomena of cell interactions in cervical cancer cells. Their findings suggest that the cells are metabolically connected in a functional network.
news-medical.net/news/20250325/Novel-global-cooperative-phenomena-of-cell-interactions-discovered-in-cervical-cancer-cells.aspx
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Fatty acids in the blood may predict risk of developing schizophrenia from cannabis use
The UPV/EHU study, recently published in the journal Scientific Reports, has analyzed and compared the fatty acids in the blood of individuals with schizophrenia, of those with cannabis use disorder and of those with both diagnoses, with the aim of shedding light on new biomarkers and improving the understanding of the biological relationship between the two disorders.
news-medical.net/news/20250321/Fatty-acids-in-the-blood-may-predict-risk-of-developing-schizophrenia-from-cannabis-use.aspx
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Natural compounds identified as potential inhibitors of SARS-CoV-2 spike protein
The COVID-19 pandemic highlighted the urgent need for effective therapeutic agents against SARS-CoV-2.
news-medical.net/news/20250320/Natural-compounds-identified-as-potential-inhibitors-of-SARS-CoV-2-spike-protein.aspx
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Scientists discover irreversible peptide inhibitors for undruggable cancer target
For the first time scientists have identified promising drug candidates that bind irreversibly with a notoriously "undruggable" cancer protein target, permanently blocking it.
news-medical.net/news/20250320/Scientists-discover-irreversible-peptide-inhibitors-for-undruggable-cancer-target.aspx
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FDA-approved drug for chronic kidney disease may help mitigate antibiotic resistance
Increased antibiotic use can lead, seemingly paradoxically, to more problematic infections, as the bacteria evolve to resist the treatment.
news-medical.net/news/20250318/FDA-approved-drug-for-chronic-kidney-disease-may-help-mitigate-antibiotic-resistance.aspx
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In the Thymus We Trust: ProTcell Therapy & the Future of Allogeneic Immunotherapy
In this interview, News Medical speaks with Olivier Negre, Chief Scientific Officer at Smart Immune, about how immunotherapy is being revolutionized.
news-medical.net/news/20250318/In-the-Thymus-We-Trust-ProTcell-Therapy-the-Future-of-Allogeneic-Immunotherapy.aspx
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Understanding how JAK inhibitors may increase blood clot risk
Why do medications that are supposed to help patients with chronic inflammatory diseases sometimes lead to blood clots?
news-medical.net/news/20250317/Understanding-how-JAK-inhibitors-may-increase-blood-clot-risk.aspx
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Mitochondria may hold key to reducing inflammaging in aging cells
In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.
news-medical.net/news/20250314/Mitochondria-may-hold-key-to-reducing-inflammaging-in-aging-cells.aspx
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Clinical trial tests herpes virus-based therapy for neurogenic bladder in people with spinal cord injury
A modified herpes virus that targets spinal cord nerve cells to treat neurogenic bladder in people with spinal cord injury is underway in a first-in-human clinical trial by UTHealth Houston at TIRR Memorial Hermann.
news-medical.net/news/20250312/Clinical-trial-tests-herpes-virus-based-therapy-for-neurogenic-bladder-in-people-with-spinal-cord-injury.aspx
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Scientists discover key molecular switch for blood stem cell regeneration
A single molecular switch is essential for blood stem cells to enter an activated, regenerative state in which they produce new blood cells, according to a preclinical study led by Weill Cornell Medicine investigators.
news-medical.net/news/20250310/Scientists-discover-key-molecular-switch-for-blood-stem-cell-regeneration.aspx
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