New research center seeks to harness the positive powers of fungi
A new research center focused on harnessing the positive powers of fungi is being established at Cranfield University with a £7.2 million injection of funding from Research England.
news-medical.net/news/20240119/New-research-center-seeks-to-harness-the-positive-powers-of-fungi.aspx
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Insilico Medicine leverages AI to identify promising new target for breast and gynecological cancers
Insilico Medicine("Insilico"), a clinical stage generative artificial intelligence (AI)-driven drug discovery company, recently published an early research that it has identified MYT1 as a promising new therapeutic target for breast and gynecological cancer, and discovered a series of novel, potent, and highly selective inhibitors specifically targeting MYT1.
news-medical.net/news/20240119/Insilico-Medicine-leverages-AI-to-identify-promising-new-target-for-breast-and-gynecological-cancers.aspx
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$2.8M grant targets copper's role in deadly kidney cancer
Copper is an essential trace element required to produce energy in the body and allows humans to live in our atmosphere.
news-medical.net/news/20240117/2428M-grant-targets-coppers-role-in-deadly-kidney-cancer.aspx
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StemSight and ERS Genomics focus on collaboration
License agreement provides StemSight access to CRISPR/Cas9 technology to be applied in development of cell therapies for corneal blindness.
news-medical.net/news/20240117/StemSight-and-ERS-Genomics-focus-on-collaboration.aspx
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Combining health data with whole genome sequence data in cancer patients can help doctors provide more tailored care
Researchers evaluated the impact of integrating whole-genome sequencing data with clinical outcomes across 13,880 tumors from 33 cancer types, assessing precision care potentials within the UK NHS through the 100,000 Genomes Cancer Programme.
news-medical.net/news/20240116/Combining-health-data-with-whole-genome-sequence-data-in-cancer-patients-can-help-doctors-provide-more-tailored-care.aspx
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When mass spectrometry redefines the pharma industry
In this new episode of omg OMx, Kate Stumpo speaks to Bruker's Mike Greig about the incredible
potential of mass spectrometry in pharma.
news-medical.net/news/20240112/When-mass-spectrometry-redefines-the-pharma-industry.aspx
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New molecule targets key protein in autoimmune diseases
Scientists from Scripps Research have developed a small molecule that blocks the activity of a protein linked to autoimmune diseases, including systemic lupus erythematosus (SLE) and Crohn's disease.
news-medical.net/news/20240111/New-molecule-targets-key-protein-in-autoimmune-diseases.aspx
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BCG vaccine's impact on innate immunity explained at cellular level
Bacillus Calmette-Guérin (BCG) is one of the world’s oldest and most widely used vaccines. It was developed in the early 20th century to provide protection from tuberculosis.
news-medical.net/news/20240109/BCG-vaccines-impact-on-innate-immunity-explained-at-cellular-level.aspx
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Using machine learning to predict disease progression in multiple sclerosis
A combination of only 11 proteins can predict long-term disability outcomes in multiple sclerosis (MS) for different individuals.
news-medical.net/news/20240109/Using-machine-learning-to-predict-disease-progression-in-multiple-sclerosis.aspx
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New approach to Parkinson's treatment focuses on stopping toxic protein production
Like the Greek mythological beast with a snake's tail and two ferocious heads, a potential Parkinson's medicine created in the lab of chemist Matthew Disney, Ph.D., is also a type of chimera bearing two heads.
news-medical.net/news/20240109/New-approach-to-Parkinsons-treatment-focuses-on-stopping-toxic-protein-production.aspx
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The equity imperative: A roundtable on transforming healthcare
In the Roundtable titled "A Glimpse at How Stakeholders Are Working Towards Achieving Health Equity," published in the peer-reviewed journal Health Equity, two expert panel discussions examine efforts to achieve maternal health equity and changes that health systems can make to operationalize health equity.
news-medical.net/news/20240109/The-equity-imperative-A-roundtable-on-transforming-healthcare.aspx
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Engineered virus-like particles power up gene editing, correcting blindness in mice
Prime editing, a versatile form of gene editing that can correct most known disease-causing genetic mutations, now has a new vehicle to deliver its machinery into cells in living animals.
news-medical.net/news/20240108/Engineered-virus-like-particles-power-up-gene-editing-correcting-blindness-in-mice.aspx
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Discovery on housekeeping genetic elements reveals a novel avenue in cancer therapy
Technological advancements have enabled scientists to comprehensively explore genetic control elements, unraveling the complexities of gene activation mechanisms in our genetic code.
news-medical.net/news/20240105/Discovery-on-housekeeping-genetic-elements-reveals-a-novel-avenue-in-cancer-therapy.aspx
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Revolutionary RNA-based switch offers new control over gene expression in mammalian cells
Researchers developed an RNA-based switch, the pA regulator system, to control gene expression in mammalian cells by modulating synthetic polyA signal cleavage, offering a novel approach for gene therapy applications.
news-medical.net/news/20240104/Revolutionary-RNA-based-switch-offers-new-control-over-gene-expression-in-mammalian-cells.aspx
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Eastern equine encephalitis virus study uncovers decoy molecule that protects against deadly brain infection
An atomic-level investigation of how Eastern equine encephalitis virus binds to a key receptor and gets inside of cells also has enabled the discovery of a decoy molecule that protects against the potentially deadly brain infection, in mice.
news-medical.net/news/20240103/Eastern-equine-encephalitis-virus-study-uncovers-decoy-molecule-that-protects-against-deadly-brain-infection.aspx
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AI scores breakthrough in anemia treatment with novel PHD inhibitor
Clinical stage generative artificial intelligence (AI)-driven biotechnology company InSilico Medicine ("InSilico"), today announced that the Journal of Medicinal Chemistry, an ACS Publications journal focusing on critical studies about molecular structure and biological activity, has published the company's discovery of a novel PHD inhibitor for the treatment of anemia.
news-medical.net/news/20240119/AI-scores-breakthrough-in-anemia-treatment-with-novel-PHD-inhibitor.aspx
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Unveiling the cellular mechanisms of engram consolidation and memory refinement
Think of a time when you had two different but similar experiences in a short period. Maybe you attended two holiday parties in the same week or gave two presentations at work.
news-medical.net/news/20240119/Unveiling-the-cellular-mechanisms-of-engram-consolidation-and-memory-refinement.aspx
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TRPC3 emerges as key player in preventing damage from alcohol-associated liver disease
Excessive alcohol intake is strongly associated with alcohol-associated liver disease (ALD) which accounts for 25% and 30% of deaths from cirrhosis and hepatocellular carcinoma. Impairment of Ca2+ influx and Ca2+-mediated signaling in ALD suggests that Ca2+ channels are important in ALD pathological progression.
news-medical.net/news/20240116/TRPC3-emerges-as-key-player-in-preventing-damage-from-alcohol-associated-liver-disease.aspx
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New USC study reveals how DNA loops silence gene activity
The blueprint for human life lies within the DNA in the nucleus of each of our cells. In human cells, around six and a half feet of this genetic material must be condensed to fit inside the nucleus. DNA condensation is not random.
news-medical.net/news/20240116/New-USC-study-reveals-how-DNA-loops-silence-gene-activity.aspx
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Pioneering Genomic Progress: An Interview with Rami Mehio, Illumina's Software and Informatics Expert
In this interview, Rami Mehio, head of software and informatics at Illumina, shares his experiences and contributions to major genomic projects like the UK Biobank's whole genome sequencing. He discusses the challenges and innovations in genomic data analysis, highlighting Illumina's role in advancing genetic research and precision medicine.
news-medical.net/news/20240115/Pioneering-Genomic-Progress-An-Interview-with-Rami-Mehio-Illuminas-Software-and-Informatics-Expert.aspx
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Scientists develop noninvasive way to monitor gene expression dynamics in the brain
Researchers introduced a non-invasive, sensitive method for monitoring gene expression in the brain using engineered reporters called released markers of activity, which can exit the brain into the blood for easy detection.
news-medical.net/news/20240112/Scientists-develop-noninvasive-way-to-monitor-gene-expression-dynamics-in-the-brain.aspx
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Revolutionary blood test monitors gene expression dynamics in the brain
The brain is the most protected organ in the body, sheathed in a complex and nearly impenetrable barrier of specialized blood vessels.
news-medical.net/news/20240111/Revolutionary-blood-test-monitors-gene-expression-dynamics-in-the-brain.aspx
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New algorithm proves to be a powerful tool for detection and identification of novel bacterial organisms
Researchers developed the NOVA algorithm to systematically analyze bacterial isolates unidentified using traditional methods such as matrix-assisted laser desorption ionization-time of flight mass spectrometry and partial 16S rRNA gene sequencing using whole genome sequencing.
news-medical.net/news/20240110/New-algorithm-proves-to-be-a-powerful-tool-for-detection-and-identification-of-novel-bacterial-organisms.aspx
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"TimeMachine" algorithm revolutionizes circadian rhythm analysis with single blood sample
"TimeMachine," an algorithm developed by U.S. researchers, accurately predicts circadian phase from a single blood sample using gene expression, offering a novel, efficient approach to understanding circadian rhythms and their impact on health.
news-medical.net/news/20240109/TimeMachine-algorithm-revolutionizes-circadian-rhythm-analysis-with-single-blood-sample.aspx
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Breakthrough in gene editing: Enhanced virus-like particles promise new era in genetic disease treatment
Researchers developed an advanced prime editor-engineered virus-like particle (PE-eVLP) system, significantly enhancing gene editing efficiency in human cells and showing potential for treating genetic diseases.
news-medical.net/news/20240109/Breakthrough-in-gene-editing-Enhanced-virus-like-particles-promise-new-era-in-genetic-disease-treatment.aspx
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Disease-causing bacteria use molecular "barcode" to distinguish between beneficial and toxic molecules
Researchers at McMaster University have discovered a molecular "barcode" system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.
news-medical.net/news/20240108/Disease-causing-bacteria-use-molecular-barcode-to-distinguish-between-beneficial-and-toxic-molecules.aspx
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Sesame protein-derived peptides show promise in fighting E. coli and S. aureus
A study in "Nutrients" reveals that sesame protein-derived peptides, Ala-Gly-Gly-Val-Pro-Arg and Ser-Thr-Ile-Arg, show effective antibacterial activity against Escherichia coli and Staphylococcus aureus.
news-medical.net/news/20240107/Sesame-protein-derived-peptides-show-promise-in-fighting-E-coli-and-S-aureus.aspx
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Metabolically armored CAR-T cells demonstrate lasting efficacy against solid tumors
At EPFL's School of Engineering, Professor Li Tang's Laboratory of Biomaterials for Immunoengineering has made significant strides in cancer treatment research.
news-medical.net/news/20240104/Metabolically-armored-CAR-T-cells-demonstrate-lasting-efficacy-against-solid-tumors.aspx
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Unmasking the persistent threats of long-COVID's pulmonary sequelae
A collaborative study led by Dr. Estefanía Nova-Lamperti of the Universidad de Concepción, Dr. Gonzalo Labarca of Harvard University, and Mauricio Hernández, of MELISA Institute, and which included the participation of researchers from leading academic institutions, sought to identify the sequelae associated with long-term pulmonary dysfunction (L-PDD) in patients with COVID-19.
news-medical.net/news/20240104/Unmasking-the-persistent-threats-of-long-COVIDs-pulmonary-sequelae.aspx
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Are pan-coronavirus vaccines an achievable goal in providing broad protection against human coronaviruses?
The current achievements in the development of a pan-coronavirus vaccine.
news-medical.net/news/20240103/Are-pan-coronavirus-vaccines-an-achievable-goal-in-providing-broad-protection-against-human-coronaviruses.aspx
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